The final and most critical step in establishing an accurate diagnosis is performing a biopsy. Imaging workup is done prior to the biopsy in order for your clinician to determine the best and most accessible region to sample within an isolated tumor. Your provider will discuss all possible methods of obtaining a tissue sample and there are several techniques available, such as:
Open incisional biopsy
A poorly performed biopsy can result in increased morbidity for a patient and may alter the possible treatment options that are available. Therefore, it is important for patients to be referred to a treatment center with an Orthopaedic Oncologist, like Dr. DiCaprio, before a biopsy is performed in order to avoid complications. Your provider will discuss which biopsy option is best for you.
Helpful information about the hazards associated with biopsy can be found on the Journal of Bone and Joint Surgery website in a study by Henry J. Mankin.