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Graduate Studies Program

First Year Graduate Courses, Fall Semester

AMC 510 - Biochemistry - 2 credits
Course Director:
Dr. Carlos de Noronha
Course Description: A major challenge to biomedical students is gaining  a better understanding of the structures, functions and interactions of molecular systems used in nature. The elucidation of protein and membrane structure, the role of enzymes in metabolic processes and cell signaling, and the modeling of life processes in the laboratory provide fundamental insights into normal physiological processes and into pathophysiological conditions. This course will provide an integrated exposure to major current concepts in biochemistry including protein structure, enzymology, membrane structure/function, and metabolism. This course covers three central themes common to all advanced courses within the various training programs: Protein Structure/Function, Biological Membranes, and Metabolism.  The first block of lectures includes the topics primarily on bioenergetics and metabolism. It will include a set of three conferences to integrate and review the material taught in each section.  AMC-510-Biochemistry, was carefully planned to integrate with "AMC-511-Molecular Cell Biology" and "AMC-515-Foundations of Biomedical Research." Together these three courses will provide MS and PhD students at AMC with the fundamentals that they will need to begin their research careers.

AMC 511 - Molecular Cell Biology - 3 credits
Course Directors:
Dr. Rebecca Keller and Dr. Richard Keller
Course Description: The overall goal of this course is to provide students with a basic understanding of molecular and cell biology and the relevance of these topics to normal and pathophysiology. This course is part of a new integrated core curriculum for all first year graduate students designated to give students the fundamentals needed for upper level graduate courses, to read primary literature, and to understand the health relevance of the basic sciences. The Learning Objectives of this course is to provide students with an understanding of the following: 

  • Mechanisms and regulation of the flow of genetic information from DNA to protein.
  • Genetics and its role in disease.
  • How cells interact with each other and their extracellular environment
  • Basic signaling cascades and the regulation of cell proliferation and survival.
  • The structural components of cells and the regulation of these components, including the cytoskeleton, intracellular compartments and vesticular trafficking.

AMC 515 - Foundations in Biomedical Research - 4 credits
Course Director:  Dr. Richard Keller
Course Description: Biomedical research builds on molecular, biochemical, cellular, and whole animal studies to understand the workings of cells, tissues, and organ systems. This course introduces students to experimental approaches using biomedical research. The goal of this course is to provide first-year graduate students with an understanding of basic experimental approaches used in biomedical research in order to jumpstart their ability to understand the primary literature and to plan and execute their own research. To this end, the course will cover the principles and theory behind currently used experimental approaches and their applications, practical details for those that are commonly used, as well as examples from the primary literature.

AMC 502 - Research Topics in the Biomedical Sciences - 1 credit
Course Director: Dr. Mark Fleck
Course Description: This literature based colloquium will introduce students to the current research in the biomedical sciences with an emphasis on the primary literature. This course will involve student presentations and round table discussions in topical areas that are being covered in AMC 515. This course is required of all first year students.

AMC 507 - Introduction to Scientific Integrity - 0 credit
Course Director:
  Dr. John Kaplan
Course Description: Students attend a total of three, two-hour class meetings and participate in workshops and discussions. Short readings will be assigned. Sessions will address current issues in scientific integrity, ethical principles and theory, introduction to ethics case analysis, an ethical skills workshop, and considerations in selecting a mentor. At the end of this course students will have a basic appreciation of ethical principles in relation to standards of professional conduct in science. Students will also develop their skills and confidence in their ability to analyze and discuss ethical and professional standards as they apply to specific aspects of scientific research. This course is required of all first year students.