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Sunday, March 30 |
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12-3 p.m. |
Hotel Registration (Reception Building) |
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12-3 p.m. |
Workshop Registration (Reception Building Sunroom) |
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3-3:30 p.m. |
Beverage Break (Conference Center, Bellvue Foyer) |
| 3:30-10:30 p.m. |
BioHealthBase: Hands on Training and Annotation (Nirvana) |
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3:30-5 p.m. |
Session I: Microbiology
(Chairs: Karl Klose and Francis Nano)
Simon L. Dove, Ph.D. (Harvard Medical School)
"Factors Influencing Expression of Francisella Pathogenicity Island
Genes"
John S. Gunn, Ph.D. (Ohio State University)
"Francisella Intramacrophage Survival: Phosphatases and Virulence
Gene Regulators"
Karl E. Klose, Ph.D. (University of Texas, San Antonio)
"Francisella tularensis Pathogenicity Island Proteins Secreted into
Macrophages"
Francis Nano, Ph.D. (University of Victoria)
"Attempts to Determine the Function of FPI-encoded Proteins" |
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5-5:30 p.m. |
Pick-up Room Key Cards (Conference Center Lobby) |
| 5:30-6:45 p.m. |
Free Time and Poster Session A Set-Up (Nirvana) |
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6:45-8:15 p.m. |
Dinner (Bellvue) |
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8:30-10:30 p.m. |
Poster Session A (Nirvana) |
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Monday, March 31 |
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7-8:30 a.m. |
Breakfast (Sagamore Dining Room) |
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| 8:30 a.m.-10 p.m. |
BioHealthBase: Hands on Training and Annotation (Nirvana) |
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8:30-10:00 a.m. |
Session II: Pathogenesis
(Chairs: Jorge Benach and Rick Lyons)
Denise M. Monack, Ph.D. (Stanford University)
"Identification of FevR, a Novel Regulator of Virulence Gene
Expression in Francisella"
Gerard J. Nau, M.D., Ph.D. (University of Pittsburgh)
"Environmental Adaptation and Francisella Pathogenesis"
David G. Thanassi, Ph.D. (Stony Brook University)
"Type IV Pili and Type I Secretion in Francisella tularensis"
Catharine M. Bosio, Ph.D. (RML/NIAID/NIH)
"The Machiavellian Nature of Type A F. tularensis" |
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10:00-10:30 a.m. |
Break (Sponsored by BD BIOSCIENCES) |
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10:30-12:00 p.m. |
Session III: Cell Biology
(Chairs: Yousef Abu-Kwaik and Jean Celli)
Marina Santic, Ph.D. (University of Rijeka)
"The Many Ways of Francisella Intracellular Trafficking"
Yousef Abu-Kwaik, Ph.D. (University of Louisville)
"Drosophila melanogaster as an Invertebrate Vector Model System
for Tularemia"
Lee-Ann H. Allen, Ph.D. (University of Iowa)
"Inhibition of Human Neutrophil Function by Francisella tularensis"
Jean Celli, Ph.D. (RML/NIAID/NIH)
"The Intracellular Transcriptome of Francisella tularensis" |
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12:15-1:30 p.m. |
Lunch (Sagamore Dining Room) |
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1:30-3 p.m. |
Session IV: Innate Immunity
(Chairs: Denise Monack and Timothy Sellati)
Meenakshi Malik, D.V.M., Ph.D. (Albany Medical College)
"Coordination of Extra- and Intra-cellular Recognition of Francisella
tularensis by Macrophages"
Thomas Henry, Ph.D. (Stanford University)
"Type I Interferon Signaling is Required for Francisella
novicida-mediated Host Cell Death and Increases Susceptibility
to Infection"
Michael Parmely, Ph.D. (University of Kansas Medical Center)
"Evasion of Innate Immunity to Type A Francisella tularensis"
Leah E. Cole, Ph.D. (University of Maryland, Baltimore)
"The Macrophage Pro-Inflammatory Response to Francisella
tularensis LVS Involves TLR2-, IFN-B-, and Capase-1-Dependent
Signaling Pathways" |
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3:00-3:30 p.m. |
Break |
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3:30-5 p.m. |
Session V: Adaptive Immunity
(Chairs: Karen Elkins and Dennis Metzger)
Siobhan C. Cowley, Ph.D. (CBER/FDA/HHS)
"T-cell Mechanisms of Controlling F. tularensis LVS Infection"
Girish S. Kirimanjeswara, D.V.M., Ph.D. (Albany Medical College)
"Exploiting the Synergy Between Cytokines and Antibodies to
Treat Tularemia"
Jeffrey A. Frelinger, Ph.D. (University of North Carolina)
"T cell Responses and Immune Evasion in Tularemia"
Wangxue Chen, Ph.D. (National Research Council)
"Immune Responses to Oral LVS Immunization and
Subsequent Respiratory Challenge with Virulent Type A
Francisella tularensis in Mice" |
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5-6:15 p.m. |
Free Time and Poster Session B Set-up (Nirvana) |
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6:15-7:45 p.m. |
Dinner (Sagamore Dining Room) |
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8-10 p.m. |
Poster Session B (Nirvana) |
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Tuesday, April 1 |
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7-8:30 a.m. |
Breakfast (Sagamore Dining Room) |
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8:30-10 a.m. |
Session VI: Proteomics/Genomics
(Chairs: David Thanassi and John Gunn)
Philip L. Felgner, Ph.D. (University of California, Irvine)
"Whole Proteome Microarrays for Vaccine and Serodiagnostic
Antigen Discovery"
Jason F. Huntley, Ph.D. (University of Texas, Southwestern)
"Francisella tularensis Outer Membrane Proteins Protect Mice
Against Pulmonary Challenge with a Type A Virulent Strain of
F. tularensis"
George Hilliard, Ph.D. (University of Tennessee, Memphis)
"Comparative Analysis of Gene Product Expression Among
Strains of F. tularensis"
Jing-Ren Zhang, D.V.M., Ph.D. (Albany Medical College)
"Screening for Francisella Virulence Factors: STM and Beyond" |
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10:00-10:30 a.m. |
Break & Hotel Check-Out (See program for more information) |
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10:30-12:00 p.m. |
Session VII: Vaccines and Therapeutics
(Chairs: J. Wayne Conlan and Anders Sjostedt)
John Belisle, Ph.D. (Colorado State University)
"Generation of Protective Immunity Against Francisella tularensis
Schu4 Using Acellular Vaccines"
Anne S. De Groot, M.D. (EpiVax, Inc., Brown University)
"High-throughput Validation of Predicted T-cell Epitopes in
F. tularensis: The Development of a Novel T-cell Epitope-based
Tularemia Vaccine"
Terry H. Wu, Ph.D. (University of New Mexico)
"Revisiting the Fischer 344 Rat Model for Tularemia"
J. Wayne Conlan, Ph.D. (National Research Council)
"New Live Vaccine Candidates to Combat Tularemia" |
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12:00-12:15 p.m. |
Summary and Future Planning |
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12:15-1:30 p.m. |
Lunch
DEPART FROM WORKSHOP |
Please note, all attendees must check-in at the Reception Building before
proceeding to the Conference Center.
