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David Botstein, PhD, director and Anthony B. Evnin Professor of Genomics, Lewis-Sigler Institute for Integrative Genomics, Princeton University, is known for proposing the concept of building a complete genetic map of the human being and identifying mapping techniques for what would eventually become the Human Genome Project.
Francis S. Collins, MD, PhD, director of the National Institutes of Health, notably developed a technique for identifying particular disease-related genes known as positional cloning, which led to the discovery of the gene that causes cystic fibrosis. Dr. Collins also provided oversight to the Human Genome Project.
Eric S. Lander, PhD, president and director of the Broad Institute of MIT and Harvard, was one of the creators of the first practical plan to make and use a comprehensive genetic map of the human genome. He also elucidated how one could develop maps of complex multiple-gene diseases such as diabetes and heart disease.